Genetics of dilated cardiomyopathy

نویسنده

  • John Solaro
چکیده

ilated cardiomyopathy (DCM), characterized by left venricular dilation and systolic dysfunction, is the most comon form of heart muscle disease, comprising 60% of the ases of identified cardiomyopathies (1). The disorder is linically heterogeneous, ranging from affected individuals ith clinical presentations of severe symptoms, including eart failure, sudden death, or resuscitated sudden death, to symptomatic individuals. The underlying etiologies of CM include ischemic heart disease, acquired disease aused by viral infection or cardiac toxins, metabolic disorers, and genetic causes. In the latter case, 30% to 40% of atients with DCM have a familial form of DCM.

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تاریخ انتشار 2016